A new study has indicated that longer someone suffers from eating disorder, anorexia nervosa, the more likely they are to show alterations in DNA methylation.
These alterations cause changes in gene expression which can affect a range of physiological mechanisms.
The study, titled “DNA methylation in individuals with Anorexia Nervosa and in matched normal-eater controls: A genome-wide study,” was led by Howard Steiger, of the Douglas Mental Health University Institute Eating Disorders Program (EDP), in Montreal, in collaboration with Linda Booij, a researcher with Sainte-Justine Hospital and an assistant professor at Queen”s University.
The study demonstrates chronicity of illness in women with anorexia nervosa to be associated with more pronounced alteration of methylation online casino levels in genes implicated in social behavior, anxiety, functioning of peripheral organs, immunity and various brain and nervous system functions, according to Steiger.
The findings entail that epigenetic mechanisms may underlie some of the consequences of anorexia nervosa that affect nervous system functioning, physical health and psychological status. If so, an intriguing possibility arises: Does remission of anorexic symptoms coincide with normalization (or resetting) of methylation levels (and could such effects provide clues to more effective treatments)?
Source: Delhi Daily News